Effectiveness and safety of DBB for sinus lift

JRCT ID: jRCTs072240100

Registered date:23/01/2025

Basic Information

• Recruitment status: Recruiting
• Health condition(s) or Problem(s) studied: Missing teeth
• Date of first enrollment: 23/01/2025
• Target sample size: 20
• Study type: Interventional
• Intervention(s): The bone substitutes used in this study will be randomly assigned to either "DBB group" or "carbonate apatite group"

Outcome(s)

Primary Outcome

Absorption rate about 5 months after sinus lift compared with after surgery by CBCT image analysis
New bone formation measured by histology

Secondary Outcome

Implant insertion torque value
ISQ value

Key inclusion & exclusion criteria

• Age minimum: >= 20age old
• Age maximum: < 90age old
• Gender: Both

Include criteria

1. Patients who want to recive dental implant treatments
2. Patients aged 20 to 90 at the time of registration
2. Patients who have loss of maxillary posteriot tooth and planned sinus lift with lateral approach
3. The vertical height of available bone is less than 3mm
4. Patients have provided written consent of their own free will to participate

Exclude criteria

1. Patients with acute or chronic inflammation at the treatment site
2. Patients with lacking the ability to make decisions
3. Patients with drug allergies
4. Pregnant women, patients who may be pregnant, or patients who are breastfeeding
5. Patients participating in clinical trials or other clinical research
6. Patients with uncontrolled metabolic diseases
7. Patients with blood disorders
8. Patients who are taking long-term steroids or immunosuppressants for autoimmune diseases
9. Patients taking bone resorption inhibitors
10. Patients undergoing radiation therapy
11. Patients who are smoking at the time of informed consent
12. Other patients deemed inappropriate by the principal investigator or subinvestigator

Related Information

• Primary Sponsor: Odatsu Tetsuro