Study of sweating function with QSART in collagen diseases

JRCT ID: jRCTs072190009

Registered date:04/06/2019

Basic Information

• Recruitment status: Complete
• Health condition(s) or Problem(s) studied: Collagen diseases
• Date of first enrollment: 01/07/2019
• Target sample size: 100
• Study type: Interventional
• Intervention(s): Acetylcholine chloride is iontophoretically applied to the skin.

Outcome(s)

Primary Outcome

Axon reflex-mediated indirect sweat volume and latency time
Raynaud's condition score

• Secondary Outcome: sex, age, disease, duration, history of digital ulcers, visceral changes, smoking, job, previous diseases, treatment, clinical data, presence of digital ulcers or pernio, degree of skin thickening, nail fold bleeding by dermoscope, presence of calcifications or telangiectasia, temprature of the fingers

Key inclusion & exclusion criteria

• Age minimum: >= 20age old
• Age maximum: Not applicable
• Gender: Both
• Include criteria: Collagen diseases (Systemic sclerosis, Mixed connective tissue disease, Systemic lupus erythematosus, Sjogren's syndrome, Dermatomyositis)

Exclude criteria

Patients who are incompatible for Ovisot.
Patients who have troubles in the forearms.
Patients who have serious allergy for dressing materials.

Related Information

• Primary Sponsor: Ashida Miwa
• Source(s) of Monetary Support: Mitsubishi Tanabe Pharma