Efficiency of transcranial direct current electrical stimulation for voice disorder

JRCT ID: jRCTs072180090

Registered date:29/03/2019

Basic Information

• Recruitment status: Complete
• Health condition(s) or Problem(s) studied: Voice disorder(Spasmodic dysphonia,essential Voice tremor, Psychogenic dysphonia)
• Date of first enrollment: 28/06/2017
• Target sample size: 5
• Countries of recruitment: United States,Japan
• Study type: Interventional
• Intervention(s): For patients with dysphonia, we will investigate whether the improvement of the speech disorder can be seen by modifying the nerve activity just below the electrodes by performing weak direct current electrical stimulation from above the scalp using a transcranial electrical stimulation device.

Outcome(s)

• Primary Outcome: Laryngeal fiber findings, auditory impression, voice inspection; vocal function test, acoustic analysis, time to count from 1 to 20, mora method, patient impairment evaluation, voice interview slip
• Secondary Outcome: Adverse event

Key inclusion & exclusion criteria

• Age minimum: >= 20age old
• Age maximum: <= 75age old
• Gender: Both

Include criteria

1. Patients with voice disorder without organic disease in the vocal cords who received the Otolaryngology Department of the University of the Ryukyus.
2. SD patients who do not hope for surgical treatment or symptom is mild,or are no indication for surgical treatment, or the patient has operated but the symptoms remain.
3. Cases in which normal speech rehabilitation was performed for more than 3 months in all cases and there was no effect.

Exclude criteria

1.Cases of brain abnormalities such as epilepsy, cerebral infarction, and brain tumor.
2.Case in which there are scars or eczema on the head skin.
3.Cases with poor physical condition on the day of examination

Related Information

• Primary Sponsor: Kiyuna Asanori
• Secondary Sponsor: Mikio Suzuki