NIPH Clinical Trials Search

JAPANESE
国立保健医療科学院
JRCT ID: jRCTs071190005

Registered date:26/04/2019

AM-AF study

Basic Information

Recruitment status Not Recruiting
Health condition(s) or Problem(s) studiedatrial fibrillation
Date of first enrollment08/10/2019
Target sample size16
Countries of recruitmentJapan
Study typeInterventional
Intervention(s)adrenomedullin arm: adrenomedullin continuous venous infusion (10 ng/kg/min, 8 hours per day) given from the day before catheter ablation to after three days of ablation (total 5 days) control arm: catheter ablation only

Outcome(s)

Primary OutcomeTotal time of significant atrial arrhythmias within 3 days after catheter ablation
Secondary Outcome1. rate of atrial arrhythmias within 3 days after catheter ablation 2. rate of atrial arrhythmias from 4 to 14 days after catheter ablation 3. inflammatory makers 4. adverse event

Key inclusion & exclusion criteria

Age minimum>= 20age old
Age maximumNot applicable
GenderBoth
Include criteriapatient receiving catheter ablation for persistent atrial fibrillation
Exclude criteria1. paroxysmal atrial fibrillation 2. significant valvular disease 3. significant heart disease (heart failure, myocardial infarction, angina etc.) 4. hyperthyroidism 5. diameter of left atria over 50 mm 6. active infection or inflammatory disease 7. malignancy

Related Information

Contact

Public contact
Name Toshihiro Kita
Address 5200 Kihara, Kiyotake, Miyazaki Miyazaki Japan 889-1692
Telephone +81-985-85-0872
E-mail toshihiro_kita@med.miyazaki-u.ac.jp
Affiliation University of Miyazaki Hospital
Scientific contact
Name Kazuo Kitamura
Address 5200 Kihara, Kiyotake, Miyazaki Miyazaki Japan 889-1692
Telephone +81-985-85-1510
E-mail kazuokit@med.miyazaki-u.ac.jp
Affiliation University of Miyazaki Hospital