Trial of prevention of preterm birth in women with prior preterm birth by vaginal progesterone

JRCT ID: jRCTs071180084

Registered date:29/03/2019

Basic Information

• Recruitment status: Complete
• Health condition(s) or Problem(s) studied: High risk for preterm birth
• Date of first enrollment: 01/11/2016
• Target sample size: 100
• Study type: Interventional
• Intervention(s): Administration of vaginal progesterone capsule (200mg/dl) once daily between 16 and 34 weeks of gestations

Outcome(s)

• Primary Outcome: Rate of preterm birth
• Secondary Outcome: NICU admission period, neonatal complications, rate of threatened preterm birth, rate of premature rupture of membrane, Fetal death, maternal adverse event

Key inclusion & exclusion criteria

• Age minimum: >= 20age old
• Age maximum: Not applicable
• Gender: Female
• Include criteria: women with prior preterm birth after second trimester

Exclude criteria

1)prior preterm birth by induction for obstetrics complication
2)contraindication of progesterone
3)multiple pregnancy
4)fetus of severe anomaly or abnormal chromosome

Related Information

• Primary Sponsor: Fujita Yasuyuki