Effects and safety of narrowband UVB irradiation on gene expression of histamine H1 receptor and allergy-related cytokine in nasal mucosa of patients with allergic rhinitis: a late phase 2 study

JRCT ID: jRCTs062230038

Registered date:19/07/2023

Basic Information

• Recruitment status: Recruiting
• Health condition(s) or Problem(s) studied: Allergic rhinitis
• Date of first enrollment: 19/07/2023
• Target sample size: 20
• Study type: Interventional
• Intervention(s): Intranasal irradiation with narrowband UVB (310nm) irradiation

Outcome(s)

• Primary Outcome: Changes in mRNA levels of histamine H1 receptor and allergy-related cytokines such as IL-4, 5 and 33
• Secondary Outcome: Nasal symptoms and macroscopic findings of nasal mucosa.

Key inclusion & exclusion criteria

• Age minimum: >= 20age old
• Age maximum: <= 64age old
• Gender: Both
• Include criteria: 1) Adult patients aged 20 or above. 2) Patients who were diagnosed as allergic rhinitis.
• Exclude criteria: 1) Patients with serious complications 2) Patients who was excluded by investigators

Related Information

• Primary Sponsor: Kitamura Yoshiaki