Effects of hydrogen jelly on depressive symptoms and cognitive function

JRCT ID: jRCTs061230041

Registered date:02/08/2023

Basic Information

• Recruitment status: Recruiting
• Health condition(s) or Problem(s) studied: Mild cognitive impairment, Depression in the elderly
• Date of first enrollment: 05/08/2023
• Target sample size: 70
• Study type: Interventional
• Intervention(s): Hydrogen-containing jelly group: Hydrogen-containing jelly is swallowed without chewing three times a day (morning, noon, night) for 28 consecutive days. Hydrogen-free jelly (placebo) group: Hydrogen-free jelly (placebo) is swallowed without chewing three times a day (morning, noon, night) for 28 consecutive days.

Outcome(s)

• Primary Outcome: Self-administered questionnaire on depressive symptoms (Beck Depression Inventory: BDI, Patient Health Questionnaire-9: PHQ-9), cognitive function test by interview (Montreal Cognitive Assessment: MoCA-J)
• Secondary Outcome: Stress assessment by voice reading (Mind Monitoring System: MIMOSIS)

Key inclusion & exclusion criteria

• Age minimum: >= 70age old
• Age maximum: Not applicable
• Gender: Both
• Include criteria: Persons over 70 years old

Exclude criteria

1. Persons who drink hydrogen water regularly
2. Persons who have gelatin allergy
3. Persons who have difficulty in swallowing

Related Information

• Primary Sponsor: Takayuki Maruyama
• Secondary Sponsor: Shinichi Tokuno,Eiji Takayama
• Source(s) of Monetary Support: Shinryo Corporation