JRCT ID: jRCTs061200002
Registered date:20/05/2020
Teprenone for preventing aggravation of COVID-19
Basic Information
Recruitment status | Not Recruiting |
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Health condition(s) or Problem(s) studied | COVID-19 |
Date of first enrollment | 15/07/2020 |
Target sample size | 100 |
Countries of recruitment | |
Study type | Interventional |
Intervention(s) | Teprenone 50mg p.o. 3 times a day after each meal for 10 days |
Outcome(s)
Primary Outcome | Intubation rate |
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Secondary Outcome | 1. Mortality 2. Period until fever relief 3. Oxygen dose 4. Change in chest CT images 5. Blood test values and theire rate of change 6. Severity 7. Period until discharge or lifting quarantine restrictions 8. Period until symptom disappearance 9. Adverse events |
Key inclusion & exclusion criteria
Age minimum | >= 20age old |
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Age maximum | Not applicable |
Gender | Both |
Include criteria | 1. 20 years-old or older 2. Confirmed diagnosis of COVID-19 with PCR or antigen test 3. temperature >= 37.5 degree Celsius 4. All subjects are required to have signed an informed consent document indicating that they understood the purpose of and procedures required for the study and are willing to participate in the study |
Exclude criteria | 1. Teprenon use within 2 weeks of study treatment 2. Patient who needs ventilator or ECMO 3. Active infectious disease requiring systemic treatment except for stable NTM 4. During pregnancy, within 28 days of postparturition, or during lactation. 5. Unidentified patient |
Related Information
Primary Sponsor | ICHIHARA Eiki |
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Secondary Sponsor | |
Source(s) of Monetary Support | Okayama University |
Secondary ID(s) |
Contact
Public contact | |
Name | Eiki ICHIHARA |
Address | 2-5-1, Shikata-cho, Kita-ku, Okayama Okayama Japan 700-8558 |
Telephone | +81-86-235-7227 |
ichiha-e@md.okayama-u.ac.jp | |
Affiliation | Okayama University Hospital |
Scientific contact | |
Name | Eiki ICHIHARA |
Address | 2-5-1, Shikata-cho, Kita-ku, Okayama Okayama Japan 700-8558 |
Telephone | +81-86-235-7227 |
ichiha-e@md.okayama-u.ac.jp | |
Affiliation | Okayama University Hospital |