Behavioral change induced by brain stimulation

JRCT ID: jRCTs052240190

Registered date:20/11/2024

Basic Information

• Recruitment status: Recruiting
• Health condition(s) or Problem(s) studied: Anorexia nervosa, Behavioral disorder
• Date of first enrollment: 20/11/2024
• Target sample size: 60
• Study type: Interventional
• Intervention(s): tDCS

Outcome(s)

• Primary Outcome: Score of Decision-making Task
• Secondary Outcome: Horizon Task, Cognitive function task (Trail making test, FAB, Stroop test), MRI, Psychological scales (EDE-Q6.0, JART, Edinburgh Handedness Inventory, SES, BITE, ECR-Go, PBI, Effortful Control, BIS/BAS, BDI-2, Locus of Control, Emotion regulation, Emotion dysregulation, AQ, COPE, BIS-11, DES, LOI, STAI, SCID-5-SPQ and PD, TOSCA)

Key inclusion & exclusion criteria

• Age minimum: >= 18age old
• Age maximum: < 60age old
• Gender: Both

Include criteria

Healthy control: 18 to 60 years of age, no histrory of psychiatric or neurological disorders, and those who have received explanation and consent.
Patients with anorexia nervosa: 18 to 60 years of age, BMI less than 18.5 and those who have received explanation and consent.
Patients with behavioral disorders other than eating disorders: 18 to 60 years of age, and those who have a diagnosis of behavioral disorders due to mental illness and have received explanation and consent.

Exclude criteria

Inability to communicate, such as significant hearing impairment. The patient has a metal object in his/her body that cannot be confirmed to be non-magnetic (aneurysm clips, mechanical prosthetic valves, nerve stimulators, insulin pumps, intraocular metal objects, etc.). Persons who are determined to be incompatible with the Transcranial Direct Current Stimulation Examination Preliminary Checklist and the MR Examination Preliminary
Checklist. Patients with claustrophobia. Women who are pregnant or may become pregnant. Women who are breast-feeding. Other subjects who are judged to be inappropriate as research subjects by the principal investigator.

Related Information

• Primary Sponsor: Isobe Masanori
• Source(s) of Monetary Support: Japan society for the promotion of science