NIPH Clinical Trials Search

JAPANESE
国立保健医療科学院
JRCT ID: jRCTs051210162

Registered date:28/01/2022

Multicenter study to evaluate the efficacy of 1L Ascorbic acid PEG plus linaclotide for bowel preparation

Basic Information

Recruitment status Not Recruiting
Health condition(s) or Problem(s) studiedpatients who require colonoscopy
Date of first enrollment12/04/2022
Target sample size1464
Countries of recruitment
Study typeInterventional
Intervention(s)Patients receive linaclotide 0.5 mg or sennoside 24 mg prior to 1-L PEG-Asc.

Outcome(s)

Primary Outcomeinadequate bowel preparation rate scored by Boston Bowel Preparation Scale (BBPS)
Secondary Outcomeprocedure-related parameters, safety and tolerability

Key inclusion & exclusion criteria

Age minimum>= 20age old
Age maximum<= 85age old
GenderBoth
Include criteria1) patients who were scheduled for elective colonoscopy 2) patients who aged over 20 years old and under 85 years old 3) patients who were able to fill in the informed consent form for participation
Exclude criteria1) severe heart failure (NYHA class III or IV) 2) severe hepatic failure (Child-Pugh C) 3) active inflammatory bowel disease 4) dementia 5) allergy to Moviprep, sennoside or linaclotide 6) advanced colorectal cancer 7) intestinal resection 8) past history of participance in this study

Related Information

Contact

Public contact
Name Akira Higashimori
Address 1-5-7 Asahi-machi, Abeno-ku, Osaka, Osaka Osaka Japan 545-8586
Telephone +81-6-6645-2121
E-mail higamo@omu.ac.jp
Affiliation Osaka Metropolitan University Hospital
Scientific contact
Name Yasuhiro Fujiwara
Address 1-5-7 Asahi-machi, Abeno-ku, Osaka, Osaka Osaka Japan 545-8586
Telephone +81-6-6645-2121
E-mail fujiwara@omu.ac.jp
Affiliation Osaka Metropolitan University Hospital