Study on reduction of salivary virus by Sodium Lauryl Diethylenediaminoglycinate on COVID-19

JRCT ID: jRCTs051210107

Registered date:13/10/2021

Basic Information

• Recruitment status: Complete
• Health condition(s) or Problem(s) studied: COVID-19 infection
• Date of first enrollment: 02/11/2021
• Target sample size: 30
• Study type: Interventional
• Intervention(s): The intervention is a gargle or a water gargle.

Outcome(s)

• Primary Outcome: The amount of virus excreted from the oral cavity by gargling is measured, and the virus removal effect from the oral cavity by gargling is confirmed. Also, evaluate the difference from water gargling.
• Secondary Outcome: The amount of virus in saliva after gargling is measured, and the effect of gargling on reducing viral shedding in saliva is evaluated.

Key inclusion & exclusion criteria

• Age minimum: >= 20age old
• Age maximum: Not applicable
• Gender: Female

Include criteria

(1) Subjects whose age at the time of obtaining consent is more than 20 years
(2) Sex; female
(3) quarantine at the hotel
(4) Meets all of 1)-3) below
1) Subjects whose Asymptomatic/mild case (without respiratory sympton nor dyspnea) has at least one RT-PCR test positive for SARS-CoV-2 from pharyng eal swab, nasopharyng eal swab or saliva.
2) Subjects who can gargle
3) Subjects who are on the first day of admission to the accommodation treatment facility and plan to perform accommodation treatment for 6 days or more
(5) Subjects who have obtained written consent voluntarily to participate in the trial

• Exclude criteria: Garg ling with sodium lauryl diethylendiaminoglycine before entry

Related Information

• Primary Sponsor: Matsuyama Akifumi
• Source(s) of Monetary Support: Saraya Co., Ltd.