Tumor-specific diagnosis of F-18 FBPA PET / CT

JRCT ID: jRCTs051190116

Registered date:04/03/2020

Basic Information

• Recruitment status: Complete
• Health condition(s) or Problem(s) studied: Patients with lesions that are difficult to distinguish between tumor and inflammation
• Date of first enrollment: 19/03/2020
• Target sample size: 100
• Study type: Interventional
• Intervention(s): Patients receive from intravenous injection of 18F-FBPA and blood collection, as well as radiation exposure from PET-CT scan.

Outcome(s)

Primary Outcome

SUV value (SUV max, SUV mean) of target lesions obtained with F-18 FBPA PET / CT
Pathological diagnosis (benign/ malignant judgment)

Secondary Outcome

Radioactivity ratio between the target lesion and the left ventricular blood pool obtained with F-18 FBPA PET / CT (Lesion / Blood ratio)
Radioactivity ratio (Lesion / Normal ratio) between target lesions and contralateral normal tissues obtained with F-18 FBPA PET / CT
Radioactivity ratio between blood radioactivity and blood pool in the left ventricular calculated from F-18 FBPA PET / CT images
The above items are evaluated and analyzed for each patient.

Key inclusion & exclusion criteria

• Age minimum: >= 20age old
• Age maximum: Not applicable
• Gender: Both
• Include criteria: Patients with lesions that are difficult to distinguish between tumor and inflammation

Exclude criteria

Pregnant women or those who wish to become pregnant
Under 20 years of age
A person who is determined to be unsuitable for participation in this study by the researcher or researcher

Related Information

• Primary Sponsor: Ono Koji