Efficacy of liver stiffness measurement by ultrasonography in pediatric liver diseases

JRCT ID: jRCTs042190056

Registered date:24/07/2019

Basic Information

• Recruitment status: Recruiting
• Health condition(s) or Problem(s) studied: Pediatric liver disease
• Date of first enrollment: 01/05/2019
• Target sample size: 200
• Study type: Observational
• Intervention(s): none

Outcome(s)

• Primary Outcome: Relationship between liver and splenic stiffness measured by SWE and autologous liver survival rate in patients with pediatric liver disease.

Secondary Outcome

Diagnostic capability of SWE for biliary atresia(BA).
Diagnosis of existence of esophageal gastric varices from the measured value of SWE at fixed points and the rate of change over time, appearance of new lesions and prediction of bleeding, other portal hypertension, cholangitis, hepato-pulmonary syndrome etc.
For liver fibrosis, correlation between measured parameters and liver biopsy results and blood data.
Difference in measured values of measured SWE and measured values in the awake state and sedation state.

Key inclusion & exclusion criteria

• Age minimum: Not applicable
• Age maximum: Not applicable
• Gender: Both
• Include criteria: All pediatric liver disease patients, including healthy controls.
• Exclude criteria: Those who disagreed participating in this study.

Related Information

• Primary Sponsor: Honda Takashi