NIPH Clinical Trials Search

JAPANESE
国立保健医療科学院
JRCT ID: jRCTs041220060

Registered date:30/08/2022

Effects on Respiratory Compliance with Sugammadex in Children on Ventilation

Basic Information

Recruitment status Complete
Health condition(s) or Problem(s) studiedPersons undergoing surgery under general anesthesia
Date of first enrollment22/09/2022
Target sample size55
Countries of recruitment
Study typeInterventional
Intervention(s)In pediatric patients undergoing general anesthesia with tracheal intubation, the EIT System Enlight 2100 is worn to observe respiratory compliance during sugammadex administration.

Outcome(s)

Primary OutcomeChanges in respiratory compliance before and after sugammadex administration
Secondary OutcomeChanges in air content distribution before and after sugammadex administration Correlation of changes in respiratory compliance with age, weight, and BMI Presence or absence of adverse events

Key inclusion & exclusion criteria

Age minimum>= 2age old
Age maximum<= 12age old
GenderBoth
Include criteria1. children between 2 and 12 years of age 2. who will undergo scheduled surgery under general anesthesia 3. who are scheduled to be intubated with muscle relaxation 4. who will undergo surgery in the supine position 5. who have obtained consent for participation in this study by signing a consent form by a surrogate
Exclude criteria1. who are allergic to rocuronium or sugammadex 2. who have respiratory complications such as asthma or active upper airway inflammation as a preoperative complication 3. Patients with skin disease in the area of the EIT 4. Persons with a chest measurement of less than 50 cm 5. Patients with upper abdominal or thoracic surgery that precludes thoracic EIT. 6. who cannot wear an EIT due to thoracic deformity 7. Patients with congenital heart disease requiring treatment 8. patients with neuromuscular diseases 9. patients with liver or kidney dysfunction 9. who have hepatic or renal dysfunction 10. other persons whom the principal investigator or subinvestigator determines are not appropriate to be included in this study

Related Information

Contact

Public contact
Name Chiharu Wakuda
Address 1-20-1,Handayama,Chuo-ku,Hamamatsu,Shizuoka Shizuoka Japan 431-3192
Telephone +81-53-435-2738
E-mail chiharu0204wakuda@yahoo.co.jp
Affiliation Hamamatsu University Hospital
Scientific contact
Name Masahiro Yagihara
Address 1-20-1,Handayama,Chuo-ku,Hamamatsu,Shizuoka Shizuoka Japan 431-3192
Telephone +81-53-435-2738
E-mail 03553840@hama-med.ac.jp
Affiliation Hamamatsu University Hospital