Efficacy of transvaginal antibiotic treatment in preventing recurrence after cystectomy for endometriomas.

JRCT ID: jRCTs041210114

Registered date:21/12/2021

Basic Information

• Recruitment status: Recruiting
• Health condition(s) or Problem(s) studied: Ovarian endometrial cyst
• Date of first enrollment: 01/02/2022
• Target sample size: 20
• Study type: Interventional
• Intervention(s): Administration of trans-vaginal antibiotics

Outcome(s)

• Primary Outcome: Recurrence rate of ovarian endometriotic cysts
• Secondary Outcome: Time to recurrence of endometriosis, Rate of adverse events, Menstrual pain and non-menstrual pain ratings (general patient assessment (VAS), general physician assessment (VAS))

Key inclusion & exclusion criteria

• Age minimum: >= 20age old
• Age maximum: <= 50age old
• Gender: Female

Include criteria

1. Patients after cystectomy for endometriomas
2. Patients who are not applicable for pseudo-menopausal therapy with hormonal treatment after cystectomy
3. Patients whose endometrium are positive for bacteria that are causative agents of ovarian endometriotic cysts
4. Written informed consent

Exclude criteria

1.Patients with hypersensitivity to metronidazole
2.Patients who continue to use GnRHa, LEP or OC as hormonal therapy for the treatment of endometriosis after surgery
3. Patients whom the doctor considers unsuitable

Related Information

• Primary Sponsor: Osuka Satoko