Clinical monitoring of Desflurane during CPB

JRCT ID: jRCTs041190132

Registered date:31/03/2020

Basic Information

• Recruitment status: Complete
• Health condition(s) or Problem(s) studied: Valvular heart disease, Ischemic heart disease
• Date of first enrollment: 31/03/2020
• Target sample size: 24
• Study type: Interventional
• Intervention(s): Blood sampling

Outcome(s)

• Primary Outcome: Blood concentration of Desflurane 30 min after administration during CPB

Secondary Outcome

Blood concentration of Desflurane 0, 5, 60 min after administration during CPB
Gas sampling of Desflurane during CPB
Blood flow volume and pressure during CPB
BIS value during CPB

Key inclusion & exclusion criteria

• Age minimum: >= 40age old
• Age maximum: <= 90age old
• Gender: Both

Include criteria

1. Valvular heart disease, Ischemic heart disease
2. Cardiopulmonary bypass with mild hypothermia
3. Age: 40~90
4. ASA PS 1~3
5. Patients with informed consent

Exclude criteria

1. Emergency surgery
2. Pregnant or breastfeedin woman
3. High degree low temperature CPB
4. %VC is below 80%
5. In case the special judgement by the researcher

Related Information

• Primary Sponsor: Suzuki Hidenori
• Source(s) of Monetary Support: Baxter Limited
• Secondary ID(s): Nil known