CD Alfacalcidol study

JRCT ID: jRCTs041180126

Registered date:23/03/2019

Basic Information

• Recruitment status: Complete
• Health condition(s) or Problem(s) studied: Crohn's disease
• Date of first enrollment: 17/06/2017
• Target sample size: 36
• Study type: Interventional
• Intervention(s): administration of alfacalcidol for patietns with active lesion of small intestine by CE and low 25OHD level.

Outcome(s)

• Primary Outcome: Percentage of groups showing endoscopic improvement after 3 months administration of Alfacalcidol (response rate)

Secondary Outcome

response rates after 3 month
endoscopic score, clinical score, clinical date, microbiota
relationship between endoscopic score and vitamin D

Key inclusion & exclusion criteria

• Age minimum: >= 18age old
• Age maximum: Not applicable
• Gender: Both

Include criteria

Crohn's disease
CDAI less than 220
no steroids use

Exclude criteria

patients with miled or severe active lesion in the colon
use of vitamin D supplement and medicine including Mg, Digitalis, PTH preparations, steroids, anti-tuberculosis drugs
pregnancy

Related Information

• Primary Sponsor: Nakamura Masanao