Optimization of adenosine stress in myocardial perfusion imaging

JRCT ID: jRCTs041180096

Registered date:14/03/2019

Basic Information

• Recruitment status: Complete
• Health condition(s) or Problem(s) studied: Healthy person
• Date of first enrollment: 26/12/2017
• Target sample size: 20
• Study type: Interventional
• Intervention(s): Drug

Outcome(s)

• Primary Outcome: To evaluate the usefulness of increased injection dose of adenosine to achieve sufficient hyperemic status under the condition of caffeine intake.

Secondary Outcome

(1) To evaluate the relationship between myocardial flow reserve determined by MRI and hemodynamic parameters including blood pressure, heart rate and cardiac output under the condition of caffeine intake.
(2) To determine the usefulness of the hemodynamic parameters to estimate hyperemia induced by adenosine under the condition of caffeine intake.

Key inclusion & exclusion criteria

• Age minimum: >= 20age old
• Age maximum: <= 39age old
• Gender: Both
• Include criteria: Healthy person

Exclude criteria

Contraindication of MRI, adenosine
Pregnant or nursing women

Related Information

• Primary Sponsor: Sakuma Hajime
• Secondary ID(s): 000029891