Effect of transcranial magnetic stimulation

JRCT ID: jRCTs032190178

Registered date:09/01/2020

Basic Information

• Recruitment status: Recruiting
• Health condition(s) or Problem(s) studied: Stroke
• Date of first enrollment: 09/01/2020
• Target sample size: 56
• Study type: Interventional
• Intervention(s): The subject is a healthy person or a patient with stroke hemiparesis. The group is divided into a group with no kinesthetic illusion induced by visual stimulation (KiNvis) therapy with only theta burst stimulation and a group with KiNvis therapy which combines the theta burst stimulation with KiNvis therapy. The stimulation conditions for the theta burst stimulation are two site: primary motor area and supplementary motor area. Physical responses are evaluated exploratory before and after intervention. The stimulation conditions for TBS are in random order. The interventions are performed for 1 day each, with a washout period more than 6 days.

Outcome(s)

• Primary Outcome: Motor Evoked Potential (MEP), Fugl-Meyer assessment (FMA), Modified Ashworth Scale (MAS)
• Secondary Outcome: Action Research Arm Test (ARAT), Stroke Impairment Assessment Set (SIAS), Motor Activity Log (MAL), Box and Block Test (BBT)

Key inclusion & exclusion criteria

• Age minimum: >= 20age old
• Age maximum: <= 80age old
• Gender: Both
• Include criteria: Healthy subjects, patient with upper function disturbance due to stroke
• Exclude criteria: Patients contraindicated for exercise therapy, patients who have metal in the brain/skull or a cardiac pacemaker

Related Information

• Primary Sponsor: Kawakami Michiyuki
• Secondary Sponsor: Kaneko Fuminari