Granulocytapheresis against severe alcoholic hepatitis

JRCT ID: jRCTs032180221

Registered date:08/03/2019

Basic Information

• Recruitment status: Suspended
• Health condition(s) or Problem(s) studied: severe alcoholic hepatitis
• Date of first enrollment: 21/11/2019
• Target sample size: 11
• Study type: Interventional
• Intervention(s): granulocytapheresis

Outcome(s)

• Primary Outcome: Outcome at 90 days after the initiation of granulocytapheresis

Secondary Outcome

the rate of normalization of white blood cells count
the rate of improvement of liver function
Safety

Key inclusion & exclusion criteria

• Age minimum: >= 20age old
• Age maximum: < 70age old
• Gender: Both

Include criteria

the patients who meet the diagnostic criteria of severe alcoholic hepatitis
the patients who are able to keep vascular access
the patients who obtained their written informed consent

Exclude criteria

the patients whose granulocyte count are below 2000
the patients who complicated with severe infection, severe heart disease, uncontrolled cancer, and end-stage liver cirrhosis
the patients who are pregnant

Related Information

• Primary Sponsor: Nakamoto Nobuhiro
• Secondary ID(s): UMIN000019351