The blood concentration of acetaminophenin and analgesic effect

JRCT ID: jRCTs031200321

Registered date:21/01/2021

Basic Information

• Recruitment status: Complete
• Health condition(s) or Problem(s) studied: Post operative pain
• Date of first enrollment: 21/01/2021
• Target sample size: 16
• Study type: Interventional
• Intervention(s): Intravenous administration of acetaminophen or physiological saline

Outcome(s)

• Primary Outcome: minimum perceived current,pain response current, blood concentration of acetaminophen
• Secondary Outcome: predicted cerebrospinal fluid concentration of acetaminophen, adverse effects

Key inclusion & exclusion criteria

• Age minimum: >= 20age old
• Age maximum: < 60age old
• Gender: Both
• Include criteria: Volunteers who understand about this study and give informed consent with free will

Exclude criteria

1) Patients who use cardiac pacemaker device
2) Expectant or nursing mothers
3) Patients who have severe hepatic impairment
4) Patients who have allergy to acetaminophen
5) Patients who have peptic ulcer
6) Patients who have hematological disorder
7) Patients who have severe kidney impairment
8) Patients who have severe cardiac dysfunction
9) Patients who have aspirin asthma
10)Patients who is judged ineligible by the doctor in charge

Related Information

• Primary Sponsor: Akiko Nishimura