Verification of effect of mouthwash for CPC formulation

JRCT ID: jRCTs031200016

Registered date:16/04/2020

Basic Information

• Recruitment status: Complete
• Health condition(s) or Problem(s) studied: Missing tooth
• Date of first enrollment: 16/04/2020
• Target sample size: 30
• Study type: Interventional

Intervention(s)

Group A: Mouthwash with colored water for about one week, and then mouthwash with CPC formulation-containing mouthwash for the same period.
Group B: Mouth washing with a CPC preparation-containing mouthwash is performed for about one week, followed by washing with colored water for the same period.

Outcome(s)

• Primary Outcome: Denture plaque attachment area and volume
• Secondary Outcome: Changes in denture plaque bacterial flora

Key inclusion & exclusion criteria

• Age minimum: Not applicable
• Age maximum: Not applicable
• Gender: Both

Include criteria

1. Patients who are visiting the Showa University Dental Hospital for dental prosthetics.
2. Patients with dentures on either upper or lower jaw at the time of consent.
3. Patients who have given written informed consent to participate in this study.

Exclude criteria

1. Patients who have a history of oral abnormalities, rash, itching or other symptoms using mouthwash.
2. Patients who are difficult to visit for any reason.
3. Patients who cannot stop drugs affecting the oral flora during the study period.
4. Other patients judged to be ineligible at the discretion of the investigator.

Related Information

• Primary Sponsor: Fuminori Iwasa
• Source(s) of Monetary Support: Earth Pharmaceutical Co., Ltd.