Topical beta-blockers for the treatment of Paronychia

JRCT ID: jRCTs031190018

Registered date:08/05/2019

Basic Information

• Recruitment status: Complete
• Health condition(s) or Problem(s) studied: Paronychia induced by EGFR inhibitors
• Date of first enrollment: 08/05/2019
• Target sample size: 50
• Study type: Interventional
• Intervention(s): Randomized

Outcome(s)

Primary Outcome

Comparison between complete response and partial response of
granuloma at week 8

Secondary Outcome

Safety and adverse effects during the trial period
Improvement of periungual erythema and granuloma at week 4
Improvement of periungual erythema and granuloma at week 8

Key inclusion & exclusion criteria

• Age minimum: >= 20age old
• Age maximum: Not applicable
• Gender: Both

Include criteria

(1) Patients over the age of 20 with Grade 2 of paronychia
caused by EGFR inhibitors
(2) Ambulatory patients can answer survey questions
(3) Patients must receive substantial and sufficient
explanation of the content of this trial in all its
aspects and provide.
(4) Patients with self-management of skin and nail care

Exclude criteria

(1) Patients with bronchial asthma, bronchospasm, chronic
obstructive pulmonary disease, and cardiac failure
(2) Patients who are deemed unsuitable for inclusion in the
study for any other reason based on the assessment by the
investigators
(3) Patients with allergy for cephem antibiotic

Related Information

• Primary Sponsor: Watanabe Tomoya