Intra-retinal arterial fibrinolysis

JRCT ID: jRCTs031180441

Registered date:28/03/2019

Basic Information

• Recruitment status: Complete
• Health condition(s) or Problem(s) studied: Central retinal artery occlusion
• Date of first enrollment: 12/11/2015
• Target sample size: 50
• Study type: Interventional
• Intervention(s): To inject tPA which concentration is prepared 8000unit/0.1ml

Outcome(s)

• Primary Outcome: Visual acuity 24 weeks after surgery

Secondary Outcome

(1)Improvement of visual acuity from baseline to 24 weeks after surgery
(2)Change of retinal thickness from baseline to 24 weeks after surgery
(3)Laser speckle from baseline to 24 weeks after surgery
(4)Occurrence rate of surgical complications
(5)Vision loss

Key inclusion & exclusion criteria

• Age minimum: >= 20age old
• Age maximum: Not applicable
• Gender: Both

Include criteria

(1)More than 20-year-old
(2)Patients with CRAO
(3)Patients who are able to stay in the hospital
(4)Patients without cardiovascular diseases
(5)Patients who obtained the informed consent

Exclude criteria

(1)Patients who may have side effects by tPA
(2)Pregnancy
(3)Patients judged to be appropriate

Related Information

• Primary Sponsor: Kadonosono Kazuaki
• Secondary ID(s): UMIN000022972