The effect of a Dried Bonito Broth on the hand-foot syndrome induced by targeted molecular therapy

JRCT ID: jRCTs031180160

Registered date:26/02/2019

Basic Information

• Recruitment status: Complete
• Health condition(s) or Problem(s) studied: Hand Foot Syndrome
• Date of first enrollment: 19/04/2019
• Target sample size: 50
• Study type: Interventional
• Intervention(s): Uptake of a dried bonito broth

Outcome(s)

• Primary Outcome: Occurrence of Hand-foot syndrome
• Secondary Outcome: Blood flow in the hands and feet; change of appetite and fatigue

Key inclusion & exclusion criteria

• Age minimum: >= 20age old
• Age maximum: Not applicable
• Gender: Both

Include criteria

1.Patients planned to be hospitalized for administration of sorafenib or regorafenib or lenvatinib molecular therapy for HCC.
2. Patients equal or over 20 years old.

Exclude criteria

1. Patients who has food allergy to fish.
2. Patients who cannot eat and drink by themselves.
3. Patients who have a history of hand foot syndrome, skin disease, neurological disieases.
4. Patients for whom the physicians decided to be inappropriate candidate.

Related Information

• Primary Sponsor: KAMIMURA KENYA
• Secondary Sponsor: Terai Shuji