Single and Multiple Dose Study of MK-7480 in Healthy Japanese Participants

JRCT ID: jRCT2071240015

Registered date:22/05/2024

Basic Information

• Recruitment status: Complete
• Health condition(s) or Problem(s) studied: Nonalcoholic fatty liver disease
• Date of first enrollment: 08/07/2024
• Target sample size: 36
• Study type: Interventional
• Intervention(s): In Part 1, a single oral dose of MK-7480 30, 90, 240, 300 mg or placebo will be administered. In Part 2, multiple oral doses of MK-7480 120 or 240 mg, or placebo will be administered once daily for 14 days.

Outcome(s)

• Primary Outcome: Safety
• Secondary Outcome: Pharmacokinetics

Key inclusion & exclusion criteria

• Age minimum: >= 18age old
• Age maximum: <= 55age old
• Gender: Both
• Include criteria: Healthy Japanese males or females aged 18 to 55 years old
• Exclude criteria: Has a history of clinically significant abnormalities or diseases

Related Information

• Primary Sponsor: Yoshitsugu Hiroyuki