NIPH Clinical Trials Search

JAPANESE
国立保健医療科学院
JRCT ID: jRCT1091220045

Registered date:31/08/2010

Effect of high dose inhaled corticosteroid on airway remodeling in asthmatic patients with IL13, STAT4, GLCCI1, CHI3L1, and other SNPs homozygote

Basic Information

Recruitment status RECRUITING
Health condition(s) or Problem(s) studiedBronchial asthma
Date of first enrollment01/02/2009
Target sample size100
Countries of recruitmentJapan
Study typeInterventional
Intervention(s)Intervention type:DRUG Name of intervention:high-dose inhaled corticosteroid Dose form / Japanese Medical Device Nomenclature:INHALANT Route of administration / Site of application:INHALATIONAL Dose per administration:400 800 microgram Dosing frequency / Frequency of use:BID everyday Planned duration of intervention:260 weeks Intended dose regimen:400 microgram bid detailes of teratment arms: Comparative intervention name:standard treatment Dose form / Japanese Medical Device Nomenclature:INHALANT Route of administration / Site of application:INHALATIONAL Dose per administration:400-800 800-1600 microgram Dosing frequency / Frequency of use:QD everyday Planned duration of intervention:260 weeks Intended dose regimen:usual use

Outcome(s)

Primary Outcomepulmonary function
Secondary OutcomeSubepithelia layer thickness and concentration of the mediators in bronchial lavage fluid

Key inclusion & exclusion criteria

Age minimum>= 18age old
Age maximumNot applicable
GenderBoth
Include criteriaBronchial asthmatic patinets
Exclude criteriacurrent smoker

Related Information

Contact

Public contact
Name Yutaka Nakamura
Address 19-1 Uchimaru, Morioka,
Telephone +81-19-651-5111
E-mail ICB75097@nifty.com
Affiliation Iwate Medical University School of Medicine
Scientific contact
Name Yutaka Nakamura
Address 19-1 Uchimaru, Morioka
Telephone +81-19-651-5111
E-mail
Affiliation Iwate Medical University School of Medicine