Relationship between sedative drugs and EEG

JRCT ID: jRCT1061230052

Registered date:23/08/2023

Basic Information

• Recruitment status: Recruiting
• Health condition(s) or Problem(s) studied: general anesthesia
• Date of first enrollment: 22/08/2023
• Target sample size: 40
• Study type: Interventional
• Intervention(s): Anesthesia is started with sevoflurane or propofol, and the sedation method is switched to the other during the surgery.

Outcome(s)

• Primary Outcome: Differences in Alpha wave power in intraoperative EEG with propofol and sevoflurane

Key inclusion & exclusion criteria

• Age minimum: >= 18age old
• Age maximum: Not applicable
• Include criteria: Patients who are at least 18 years of age and scheduled to undergo scheduled surgery, with a scheduled surgery time of at least 5 hours.

Exclude criteria

Patients with an American Society of Anesthesiologists physical status (ASA-PS) score of 3 or higher
Emergency surgery
Patients with preoperative cognitive dysfunction Patients taking antipsychotic medications
Patients with drug or alcohol dependence
Patients with a history of cerebral infarction, cerebral hemorrhage, or neurosurgery
Patients who cannot have an EEG monitor placed on the forehead due to trauma or skin disorders

Related Information

• Primary Sponsor: Iwata Hideki