Expression of genes associated with type 2 inflammation in eosinophilic sinusitis.

JRCT ID: jRCT1060230017

Registered date:21/05/2023

Basic Information

• Recruitment status: Pending
• Health condition(s) or Problem(s) studied: nasal sinus disease
• Date of first enrollment: 21/05/2023
• Target sample size: 200
• Study type: Observational

Outcome(s)

• Primary Outcome: Gene expression associated with nasal mushrooms and type 2 inflammation of the nasal sinus mucosa collected from patients' nasal sinus tissue will be analyzed for patients with eosinophilic sinusitis and other patients. Gene expression analysis will be identified using real-time PCR.

Key inclusion & exclusion criteria

• Age minimum: >= 18age old
• Age maximum: Not applicable
• Gender: Both

Include criteria

Patient Groups
1. patients who have been determined to be candidates for surgical treatment of eosinophilic sinusitis
2. Adult patients who have listened to the explanation of the study and given their consent.

Control group
1. patients with rhinosinus diseases other than eosinophilic sinusitis for which surgical treatment is indicated
2. adult patients who have listened to the study description and have given their consent

Exclude criteria

1. Patients under 18 years old
2. pregnant women

Related Information

• Primary Sponsor: Kitamura Yoshiaki