Development and validation for visualisation of the non-linear correlation between age and clinical outcome in patients with aneurysmal subarachnoid haemorrhage

JRCT ID: jRCT1060210092

Registered date:30/03/2022

Basic Information

• Recruitment status: Recruiting
• Health condition(s) or Problem(s) studied: Aneurysmal subarachnoid hemorrhage
• Date of first enrollment: 01/01/2000
• Target sample size: 8000
• Study type: Observational

Outcome(s)

• Primary Outcome: modified Rankin Scale (mRS) score at discharge

Key inclusion & exclusion criteria

• Age minimum: >= 18age old
• Age maximum: <= 89age old
• Gender: Both
• Include criteria: patients age between 18 and 89 years old, pre-event modified Rankin Scale score 0-2, saccular aneurysm, normal size aneurysm, and ruptured saccular single aneurysm and patients treated via surgical clipping or endovascular coiling within 3 days after onset.
• Exclude criteria: patients with dissecting aneurysms, infectious or traumatic pseudo-aneurysms, giant aneurysms, or aneurysms of an unknown or unrecorded origin; patients with missing data for any of the analyzed variables; patients who only received cerebrospinal fluid drainage, conservative management, wrapping, trap and bypass surgery for unusual aneurysms, or proximal parent artery occlusion; patients with a pre-event modified Rankin Scale score 2-5 and patients who were not treated within 3 days after onset.

Related Information

• Primary Sponsor: IKAWA FUSAO
• Source(s) of Monetary Support: This study was funded by the Pfizer Health Research Foundation Japan 2019 19-E 01 and the Japan Society for the Promotion of Science Grant in Aid for Scientific Research C 17K10829.