Effect of resistance training on skeletal muscle quality and brain function for patients with knee osteoarthritis

JRCT ID: jRCT1052210143

Registered date:26/12/2021

Basic Information

• Recruitment status: Recruiting
• Health condition(s) or Problem(s) studied: Knee osteoarthritis
• Date of first enrollment: 17/12/2021
• Target sample size: 90
• Study type: Interventional
• Intervention(s): Patients undergo twice per week resistance training programme for a twelve-week. Resistance training of two types are applied; Power training (high speed) and conventional training (low speed). These interventions are performed on the quadriceps with a weight.

Outcome(s)

• Primary Outcome: Muscle quarity and quantity
• Secondary Outcome: Muscle strength, Knee function, Gait function

Key inclusion & exclusion criteria

• Age minimum: >= 50age old
• Age maximum: Not applicable
• Gender: Female

Include criteria

Woman diagnosed with knee OA based on X-ray findings by a doctor
Patients who have the ability to walk without assistive devices

Exclude criteria

Patients with rheumatoid arthritis, spontaneous osteonecrosis of the knee.
Patients with a surgical or fracture history for lower limbs.
Patients with cardiovascular disorders that significantly affect gait function.
Patients with a history for mental and neurological disorders.
Patients who have contraindications for MRI measurement.

Related Information

• Primary Sponsor: Kobayashi Masashi