Transfer of aspartyl dipeptide in Hatcho Miso into blood and blood pressu re variability

JRCT ID: jRCT1051230143

Registered date:13/12/2023

Basic Information

• Recruitment status: Recruiting
• Health condition(s) or Problem(s) studied: Healthy subjects
• Date of first enrollment: 13/12/2023
• Target sample size: 10
• Study type: Interventional

Intervention(s)

Group A: 1st Miso; take 18 g orally with 180ml of hot water. 2nd Salt; take 2g orally with 180 ml of hot water.
Group B: 1st Salt; take 2g orally with 180 ml of hot water. 2nd Miso; take 18 g orally with 180ml of hot water.

Outcome(s)

• Primary Outcome: Aspartyl dipeptide concentration before and and after ingestion of Hatcho Miso
• Secondary Outcome: Blood pressure, plasma renin activity and aldosterone levels, aspartyl dipeptide concentration before and after ingestion of salt, and safety

Key inclusion & exclusion criteria

• Age minimum: >= 18age old
• Age maximum: Not applicable
• Gender: Both
• Include criteria: Healthy subjects

Exclude criteria

Those who are undergoing regular medical examinations by a physician for hypertension, arrhythmia, or renal disease.
Pregnant or possibly pregnant. Those who are breast-feeding.
Those who are allergic to soybeans.
Those who the principal investigator or research coordinator determines to be inappropriate to conduct this study.

Related Information

• Primary Sponsor: Ikeda Kaori