Inhibitory effects of high-concentration fluoride on hypersensitivity and caries progression against the initial active root caries lesions: A randomized controlled trial

JRCT ID: jRCT1051220182

Registered date:02/03/2023

Basic Information

• Recruitment status: Recruiting
• Health condition(s) or Problem(s) studied: initial active root caries
• Date of first enrollment: 02/03/2023
• Target sample size: 20
• Study type: Interventional
• Intervention(s): application of 2 % sodium fluoride solution or 22600rpm fluoride varnish

Outcome(s)

• Primary Outcome: hardness of the root dentin
• Secondary Outcome: symptom of hypersensitivity

Key inclusion & exclusion criteria

• Age minimum: >= 20age old
• Age maximum: Not applicable
• Gender: Both
• Include criteria: Adults who have initial active root caries with hypersesitive symptom.
• Exclude criteria: Patients with significant reduction in salivary flow due to drug side effects, diabetes, Sjogren's syndrome, radiation therapy and so on.

Related Information

• Primary Sponsor: Hayashi Mikako