Randomized study comparing Baloxavir Marboxil to Peramivir in pediatric patients with Influenza

JRCT ID: jRCT1051180014

Registered date:17/12/2018

Basic Information

• Recruitment status: Pending
• Health condition(s) or Problem(s) studied: Influenza
• Date of first enrollment: 12/12/2018
• Target sample size: 40
• Study type: Interventional

Intervention(s)

Interventions 1
Baloxavir marboxil
Interventions 2
Peramivir

Outcome(s)

Primary Outcome

The time to alleviation of influenza symptoms
The time to resolution of fever

• Secondary Outcome: The changes from baseline in infectious virus and viral RNA titers

Key inclusion & exclusion criteria

• Age minimum: none
• Age maximum: 15 years old
• Gender: Both

Include criteria

1)axillary temperature more than 37.5 degree
2)a positive rapid antigen test for influenza virus
3)a symptom duraiton of no more than 36 hours
4)hospitalized patient
5)body weight more than 10kg

Exclude criteria

1)patients who have suffered from bacterial infection or other viral infection within one week from the start of the study
2)patients who received recipes of Baloxavir marboxil, Oseltamivir, Zanavivir, Laninavir, Peramivir within 4 weeks from the start of the study

Related Information

• Primary Sponsor: Kato Kentaro