QSP model building in patients with atopic dermatitis after treatment with nemolizumab

JRCT ID: jRCT1050240261

Registered date:05/02/2025

Basic Information

• Recruitment status: Not Recruiting
• Health condition(s) or Problem(s) studied: Atopic dermatitis
• Date of first enrollment: 05/02/2025
• Target sample size: 338
• Study type: Observational

Outcome(s)

• Primary Outcome: This study will perform modeling a mathematical model using laboratory values and clinical scores of healthy people and AD patients. The goodness of fit of the model is assessed using an evaluation value calculated from the difference between predicted and measured values when adjusting the model parameters.

Key inclusion & exclusion criteria

• Age minimum: >= 13age old
• Age maximum: <= 80age old
• Gender: Both
• Include criteria: Various information (subject background, laboratory values, clinical scores, etc.) obtained in clinical studies in AD patients and healthy subjects (jRCT2080223684, jRCT2080223838, jRCT2080225290, jRCT1030230474) and, where appropriate, in vitro and in vivo data will be used.
• Exclude criteria: Various information (subject background, laboratory values, clinical scores, etc.) obtained in clinical studies in AD patients and healthy subjects (jRCT2080223684, jRCT2080223838, jRCT2080225290, jRCT1030230474) and, where appropriate, in vitro and in vivo data will be used.

Related Information

• Primary Sponsor: Fujita Tomoyuki