Retinal image analysis using adaptive optics devices

JRCT ID: jRCT1050230199

Registered date:11/03/2024

Basic Information

• Recruitment status: Recruiting
• Health condition(s) or Problem(s) studied: retinochoroidal diseases, retinitis pigmentosa, glaucoma, uveiti .etc
• Date of first enrollment: 15/02/2024
• Target sample size: 220
• Study type: Observational

Outcome(s)

Primary Outcome

1) Morphological observation and quantitative evaluation of photoreceptor cells (cell density, etc.) using m2OCT
2) Morphological observation and quantitative evaluation of retinal pigment epithelial cells using TFI-rtx1 (cell density, etc.)
3) Comparison of captured images of rtx1 and TFI-rtx1

Key inclusion & exclusion criteria

• Age minimum: >= 20age old
• Age maximum: Not applicable

Include criteria

1. Subjects
(1) patients with retinochoroidal diseases, (2) patients with retinitis pigmentosa, (3) patients with glaucoma,
(4) patients with uveitis, (5) patients scheduled for transplantation of iPS cell-derived retinal cells, (6) patients after iPS cell-derived retinal cell transplantation. In addition, (7) healthy volunteers will be used to photograph normal eyes.
2. Selection criteria
(1) Persons 20 years of age or older.
(2) Persons who have consented to participate in this research.

Exclude criteria

(1) Persons judged by the principal researcher to be inappropriate as research subjects
(2) The following persons fall under the contraindications and prohibitions of using the AO fundus imaging device:
Those with a history of photosensitivity; those who have recently received photodynamic therapy (PDT) (Please refer to the package insert of the photosensitive substance administered for the prohibited period);those who are taking medicines that may cause photosensitivity

Related Information

• Primary Sponsor: Mandai Michiko