Development of Early Diagnosis of Pancreatic Cancer by Liquid Biopsy

JRCT ID: jRCT1042240125

Registered date:20/11/2024

Basic Information

• Recruitment status: Recruiting
• Health condition(s) or Problem(s) studied: Pancreatic cysts, chronic pancreatitis, familial pancreatic cancer, diabetic cases, etc.
• Date of first enrollment: 12/06/2023
• Target sample size: 600
• Study type: Observational

Outcome(s)

• Primary Outcome: Search for effective biomarkers for early diagnosis of pancreatic cancer
• Secondary Outcome: Investigating the association between pancreatic cancer development and pancreatic parenchymal lipidisation in high-risk cases of pancreatic cancer.

Key inclusion & exclusion criteria

• Age minimum: >= 20age old
• Age maximum: Not applicable
• Gender: Both

Include criteria

1. Cases diagnosed as high-risk group for pancreatic cancer who visited Fujita Medical University Hospital;cases with pancreatic cysts, chronic pancreatitis, familial pancreatic cancer and hereditary pancreatic cancer family history, diabetic cases (new onset and acute exacerbation), cases of localised pancreatic atrophy (localised pancreatic duct stenosis) and cases of severe pancreatic lipidosis are defined as high risk group for pancreatic cancer.
2. Pancreatic cancer cases
3. Age 20 years or older at time of enrolment
4. Cases that do not meet the indications for surgery in pancreatic tumors at the time of diagnosis
5. Cases with preserved major organ function
6. Cases in which the patient's consent to participate in this study has been obtained

Exclude criteria

1. Post-Pancreatic Surgery Cases
2. Cases with serious complications
3. Cases deemed ineligible by the physician
4. Cases with pancreatic pseudocysts associated with pancreatitis
5. Patients with overlapping cancers on ongoing treatment at the time of enrollment

Related Information

• Primary Sponsor: Hirooka Yoshiki