Metabolic changes by niacin

JRCT ID: jRCT1041230130

Registered date:11/01/2024

Basic Information

• Recruitment status: Recruiting
• Health condition(s) or Problem(s) studied: Healthy subjects
• Date of first enrollment: 11/01/2024
• Target sample size: 20
• Study type: Interventional

Intervention(s)

Taking supplements
1) NMN250mg
2) NMN125mg
3) Nicotinamide 250mg
4) Nicotinic acid 50mg

Outcome(s)

• Primary Outcome: Change in urinary metabolite levels after taking supplements
• Secondary Outcome: Change in bood metabolite levels after taking supplements

Key inclusion & exclusion criteria

• Age minimum: >= 18age old
• Age maximum: Not applicable
• Gender: Both

Include criteria

1) Healthy subjects
2) Young adults (18 to 29 years of age) and middle-aged and older adults (50 years of age or older)
(3) Individuals who have given their free and voluntary written consent to participate in the study after obtaining sufficient informed consent.

Exclude criteria

(1) Pregnant, lactating, or possibly pregnant
(2) Those taking medicines or supplements containing nicotine, nicotinic acid, or NMN.
(3) Those with a history of hypersensitivity to medicines containing nicotine, nicotinic acid, or NMN, or to various foods containing nicotine, nicotinic acid, or NMN supplements.
(4) Those who are deemed inappropriate as research subjects by the Principal Investigator for other reasons.

Related Information

• Primary Sponsor: Hirao Atsushi