Comparison of therapeutic effects of denosumab and romosozumab using Propensity Score Matching in postmenopausal osteoporosis patients

JRCT ID: jRCT1041200090

Registered date:06/01/2021

Basic Information

• Recruitment status: Recruiting
• Health condition(s) or Problem(s) studied: Primary osteoprosis
• Date of first enrollment: 01/04/2018
• Target sample size: 150
• Study type: Observational

Outcome(s)

• Primary Outcome: Bone density chang e (lumbar spine)
• Secondary Outcome: Bone density(total hip, femoral neck),Bone metabolic marker

Key inclusion & exclusion criteria

• Age minimum: >= 45age old
• Age maximum: <= 100age old
• Gender: Female
• Include criteria: primary osteoporosis

Exclude criteria

1. Previous romosozumab or denosumab use.
2. hypocalcemia
3. Cardiovascular events within 1 year
4. Pregnant or lactating women, those who wish to become pregnant
5. Patients judg ed to be inappropriate for study

Related Information

• Primary Sponsor: Kobayakawa Tomonori