JRCT ID: jRCT1041200085
Registered date:25/12/2020
Analysis of Liposomal irinotecan's pharmacokinetics and side effects
Basic Information
| Recruitment status | Recruiting |
|---|---|
| Health condition(s) or Problem(s) studied | Pancreatic cancer |
| Date of first enrollment | 25/12/2020 |
| Target sample size | 15 |
| Countries of recruitment | |
| Study type | Observational |
| Intervention(s) |
Outcome(s)
| Primary Outcome | Comparison of drug concentration of Irinotecan and its metabolites by UGT1A1 gene polymorphism |
|---|---|
| Secondary Outcome | Secondary Outcome(s)Adverse events, Time to treatment failure, Effectiveness (Response rate, progression-free survival, Overall survival) |
Key inclusion & exclusion criteria
| Age minimum | >= 20age old |
|---|---|
| Age maximum | Not applicable |
| Gender | Both |
| Include criteria | Pancreatic cancer, underwent UGT1A1 polymorphism test |
| Exclude criteria | Already used Onivyde(Liposomal irinotecan) |
Related Information
| Primary Sponsor | ANDO Yuichi |
|---|---|
| Secondary Sponsor | |
| Source(s) of Monetary Support | |
| Secondary ID(s) |
Contact
| Public contact | |
| Name | Satoshi FURUNE |
| Address | 65 Tsurumai-cho Showa-ku,Nagoya, Aichi Aichi Japan 466-0065 |
| Telephone | +81-527442172 |
| s-furune@med.nagoya-u.ac.jp | |
| Affiliation | Nagoya University Hospital |
| Scientific contact | |
| Name | Yuichi ANDO |
| Address | 65 Tsurumai-cho Showa-ku,Nagoya, Aichi Aichi Japan 466-0065 |
| Telephone | +81-527442172 |
| yando@med.nagoya-u.ac.jp | |
| Affiliation | Nagoya University Hospital |