DGC Residual Effects Study

JRCT ID: jRCT1040230048

Registered date:24/06/2023

Basic Information

• Recruitment status: Recruiting
• Health condition(s) or Problem(s) studied: male infertile patient
• Date of first enrollment: 24/06/2023
• Target sample size: 40
• Study type: Observational

Outcome(s)

• Primary Outcome: Semen findings before DGC treatment (fluid volume, total sperm concentration, motility rate, malformation rate, and SDF rate) and immediately after DGC treatment and after 4 hours of incubation (semen volume, total sperm concentration, motility rate, malformation rate, and SDF rate)
• Secondary Outcome: The residual solution after DGC treatment and additional washings were performed and the effects on semen findings and SDF immediately after treatment and after 4 hours of incubation were evaluated using detailed parameters obtained during general semen/sperm tests (pH, LIN (linearity), STR (linearity), WOB (curvature), VAP (mean velocity), VSL (velocity of curvature), VCL (velocity of straight line), ALH (head amplitude value), BCF (head amplitude frequency), Head Length (length of sperm head), Head Width (width of sperm head), Head Length (length of sperm head), Head Length (length of sperm head), Head Width (length of sperm head), and Head Length (width of sperm head)). ), ALH (head amplitude value), BCF (head amplitude frequency), Head Length (length of sperm head), Head Width (width of sperm head), Head Perimeter (circumference of sperm head), Head Area (area of sperm head), Tail Length

Key inclusion & exclusion criteria

• Age minimum: >= 18age old
• Age maximum: Not applicable
• Gender: Male

Include criteria

1) Male patients over 18 years old
2) Patients whose background can be confirmed in the medical records
3) Patients with a total sperm concentration of 2.0 x 10^6 /ml or higher and a motility rate of 40% or higher in the original semen
4) Patients who have given written consent to participate in the study.

Exclude criteria

1) Those with severe oligozoospermia, severe spermatasthenia, severe hypospermia or azoospermia
2) Patients who are deemed inappropriate for inclusion in the study by the principal investigator or research coordinator.

Related Information

• Primary Sponsor: Maezawa Tadashi