The Neural Basis of Higher-Order Cognitive Development in Childhood: An Investigation Using Functional Near Infrared Spectroscopy (fNIRS)

JRCT ID: jRCT1040220076

Registered date:18/10/2022

Basic Information

• Recruitment status: Recruiting
• Health condition(s) or Problem(s) studied: Typical development
• Date of first enrollment: 18/10/2022
• Target sample size: 120
• Study type: Observational

Outcome(s)

• Primary Outcome: Performance on cognitive tasks (accurracy), Cortical activation indices using fNRIS (i.e., oxygenated hemoglobin (oxy-Hb), deoxygenated hemoglobin (deoxy-Hb) change and total hemoglobin (total-Hb) change)

Secondary Outcome

Performance on cognitive tasks (Reaction Times)
The result of Behavior Rating Inventory of Executive Function, Psychological
Assessment Resources

Key inclusion & exclusion criteria

• Age minimum: >= 5age 1weeks old
• Age maximum: < 13age old
• Gender: Both

Include criteria

Persons who meet all of the following criteria are eligible:
1. Children between 5 and 12 years of age.
2. Persons who consent to participate in this study by themselves and the caregiver.

Exclude criteria

Patients who meet any of the following criteria will not be included in this study.
1. Persons with visual abnormalities
2. Those who have brain diseases, cerebrovascular disease or neurodegenerative disease.
3. Those who have psychiatric disorders.
4. Those who have neurological disorders (i.e., epilepsy )
5. Those whose intellectual level (IQ) assessed using WISC (Wechsler Intelligence Scale for Children) is less than 80.
6. Children who do not meet the criteria to be classified as typically developing children on the Day-1 results(children who are below the cut-off thresholds for ASD and ADHD assessment and do not meet DSM 5 diagnostic criteria)
7. Other, persons deemed by the investigator to be inappropriate to participate in this study.

Related Information

• Primary Sponsor: HARADA Taeko