A study to investigate the relationships between exercise and the renin-angiotensin system in the kidney

JRCT ID: jRCT1040210055

Registered date:18/08/2021

Basic Information

• Recruitment status: Recruiting
• Health condition(s) or Problem(s) studied: CKD
• Date of first enrollment: 18/08/2021
• Target sample size: 60
• Study type: Interventional
• Intervention(s): Exercise therapy is performed for 3 mmonths in the outpatient clinic once a week and at home in the remaining 6 days a week.

Outcome(s)

• Primary Outcome: Urinary angiotensinogen excretion rate and the change rate of it

Secondary Outcome

Urinary albumin excretion rate and the change rate of it
Urinary protein excretion rate and the change rate of it
Number of steps and the change rate of it
Calories burned and the change rate of it
Muscle strength and the change rate of it
Muscle mass and the change rate of it
Adverse events

Key inclusion & exclusion criteria

• Age minimum: >= 20age old
• Age maximum: Not applicable
• Gender: Both

Include criteria

1. Patients over 20 years
2. CKD patients
3. Patients who have undergone total hip arthoplasty
4. Patients who have obtained the consent for this study by signing the consent form.

Exclude criteria

1. CKD patients undergoing dialysis or kidney transplantation
2. Patients using immunosuppressants and RAS inhibitors that affect renal damage and renal RAS activity.
3. Patients whose exercise is prohibited due to heart or brain disease

Related Information

• Primary Sponsor: Ohashi Naro