Effect of food sequence on blood glucose in healthy participants.

JRCT ID: jRCT1032230273

Registered date:01/08/2023

Basic Information

• Recruitment status: Not Recruiting
• Health condition(s) or Problem(s) studied: Healthy Volunteers
• Date of first enrollment: 07/08/2023
• Target sample size: 18
• Study type: Interventional
• Intervention(s): During the first 10 minutes of the meal, carbohydrate intake should be limited as much as possible. After 10 minutes, the remainder of the meal should be eaten as usual. Besides minimizing carbohydrate intake during the first 10 minutes, there is no intervention or restriction on overall food intake or nutritional balance.

Outcome(s)

• Primary Outcome: Incremental glucose peak

Secondary Outcome

Association between nutrient intakes and incremental glucose peak.
Time-in-range.
The area under the continuous glucose monitoring curve.
Glucose drop.

Key inclusion & exclusion criteria

• Age minimum: >= 18age old
• Age maximum: Not applicable
• Gender: Both

Include criteria

Over the age of 18.
No history of diabetes (type 1 or type 2) or endocrine disorders.
Subjects must have undergone a physical examination within the past two years, and the most recent results show fasting blood glucose less than 100 mg/dl and hemoglobin A1c less than 5.6% (if only either one of the measurements is available, the subject is considered to meet the criteria; if neither measurement is available, the subject is deemed ineligible).
Can prepare a smartphone compatible with the continuous glucose monitoring device.
Can calculate nutritional intake using Smart Nutrition Calculator Ver. 6.0 or higher (Medical and Dental Publishing, Tokyo, Japan).

Exclude criteria

A family history of diabetes.
BMI of 35 (kg/m^2) or higher.
Pregnant or breastfeeding mothers.
Have been diagnosed with depression, adjustment disorder, bipolar disorder, or schizophrenia.
On a restricted diet as directed by their healthcare provider.
Taking corticosteroids.
Taking thiazide diuretics.
Taking hydroxycarbamide.
A history of dermatitis or skin tears caused by adhesive products such as tape.
A history of contact dermatitis.
Metal allergy.
A history of anaphylaxis.

Related Information

• Primary Sponsor: Nakamura Sho