Skin graft healing rate on biofilm detection

JRCT ID: jRCT1032220021

Registered date:13/04/2022

Basic Information

• Recruitment status: Recruiting
• Health condition(s) or Problem(s) studied: Skin defect from chronic wounds or burns
• Date of first enrollment: 05/07/2022
• Target sample size: 20
• Study type: Interventional
• Intervention(s): Using Biofilm Detection Tools in Skin Transplantation Surgery

Outcome(s)

• Primary Outcome: Percentage of skin graft healing obtained at 14 days post-implantation that grew in the area where biofilm detection sheets were used for grafting.

Secondary Outcome

Complications
Biofilm Positive Rate
Differences in skin graft healing rates in populations that were initially positive for biofilm and those that were initially negative

Key inclusion & exclusion criteria

• Age minimum: >= 20age old
• Age maximum: Not applicable
• Gender: Both

Include criteria

1) Patients with chronic wounds that have not healed for more than one month or burns with Body Surface Area 3 percent or more
2) Patients undergoing split thickness skin graft for skin defect
3) Patients aged 20 years or older at the time of obtaining consent
4) Patients who have received sufficient explanation and understanding of the study, and have given their free written consent to participate in the study

Exclude criteria

1) Patients taking the following medications
Steroids,azathioprine,cyclophosphamide,cyclosporine,tacrolimus, mycophenolate mofetil, mizoribine, methotrexate, leflunomide
2) Patients diagnosed with malignant rheumatoid arthritis, scleroderma, systemic lupus erythematosus, dermatomyositis
3)Other patients who are judged by the research physician to be unsuitable as test subjects.

Related Information

• Primary Sponsor: Aihara Yukiko
• Source(s) of Monetary Support: Grants-in-Aid for Scientific Research