PRT for skull base chordoma and chondrosarcoma.

JRCT ID: jRCT1032180086

Registered date:17/01/2019

Basic Information

• Recruitment status: Recruiting
• Health condition(s) or Problem(s) studied: Skull base chordoma or chondrosarcoma
• Date of first enrollment: 22/03/2019
• Target sample size: 60
• Study type: Interventional
• Intervention(s): Proton Radiation Therapy

Outcome(s)

• Primary Outcome: 3 year local recurrence free survival
• Secondary Outcome: 5 or 10 year local recurrence free survival, Late toxicity

Key inclusion & exclusion criteria

• Age minimum: >= 15age old
• Age maximum: Not applicable
• Gender: Both

Include criteria

1, Pathological diagnosis is chordoma or chondrosarcoma
2, General condition is maintained (PS 0-2 or PS 3 caused by tumor)
3, When tumor is controlled,5-year survival is expected.
4, Obtain written informed consent.
5, 15 years old or more.

Exclude criteria

1, Multiple primary cancers
2, Invasion for brain stem or optic chiasm
3, Distant metastases
4, Active infectious meningitis
5, Pregnant, unwilling to practice contraception during study, or lactating female.
6, Not suitable for participation by mental illnesses
7, Difficult to participate by the judgment of a doctor

Related Information

• Primary Sponsor: Sakurai Hideyuki