Prediction of therapeutic efficacy for intestinal inflammation by microbiome

JRCT ID: jRCT1031240594

Registered date:06/01/2025

Basic Information

• Recruitment status: Recruiting
• Health condition(s) or Problem(s) studied: Inflammatory Bowel Disease,
• Date of first enrollment: 01/12/2021
• Target sample size: 400
• Study type: Observational
• Intervention(s): collecting stool sumples

Outcome(s)

• Primary Outcome: intestinal microbiome
• Secondary Outcome: NA

Key inclusion & exclusion criteria

• Age minimum: Not applicable
• Age maximum: Not applicable
• Gender: Both

Include criteria

1) Ulcerative colitis and Crohn's disease diganosed by clinical, radiological, endoscopical, and pathological findings.
2) Clinically required to start biological agents.
3) Obtained written concent.

Exclude criteria

1) Individuals who stopped threatment due to adverse events or unexpected reactions.
2) Individuals who were started corticosteroid treatment within 16 weeks of biologics induction.
3) Individuals who were taking antibiotics at the time of stool sumpling.

Related Information

• Primary Sponsor: Fukata Masayuki
• Source(s) of Monetary Support: Japan Community Hearth care Oraganization
• Secondary ID(s): NA