JRCT ID: jRCT1031220071
Registered date:19/05/2022
Study comparing efficacy of two types of zoster vaccines in HIV positive people
Basic Information
Recruitment status | Pending |
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Health condition(s) or Problem(s) studied | zoster |
Date of first enrollment | 19/05/2022 |
Target sample size | 200 |
Countries of recruitment | |
Study type | Interventional |
Intervention(s) | Participants will be allocated either to Shingrix (recombinant zoster vaccine/GSK) or Varicella vaccine (live attenuated vaccine/Takeda, Tanabe Mitsubishi, Osaka University). |
Outcome(s)
Primary Outcome | developing zoster |
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Secondary Outcome | serum VAV-IgG titer and skin reaction to varicella virus antigen after the vaccination adverse events after the vaccination |
Key inclusion & exclusion criteria
Age minimum | >= 50age old |
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Age maximum | Not applicable |
Gender | Both |
Include criteria | 1. 50 or over 50 years old 2. HIV positive with CD4 counts 200 or more than 200 per microliter 3. written informed consent |
Exclude criteria | 1. history of severe allergic reaction to the vaccine ingredient 2. severely immunocompromised 3. history of vaccination against varicella or zoster within 5 years 4. reagarded as inappropriate by the study investigators |
Related Information
Primary Sponsor | Yoshimura Yukihiro |
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Secondary Sponsor | |
Source(s) of Monetary Support | |
Secondary ID(s) |
Contact
Public contact | |
Name | Yukihiro Yoshimura |
Address | 1-1 Mitsuzawanishi-cho Kanagawa-ku Yokohama city Kanagawa Kanagawa Japan 221-0855 |
Telephone | +81-45-316-4580 |
yymolep@gmail.com | |
Affiliation | Yokohama Mucnicipal CItizen's Hospital |
Scientific contact | |
Name | Yukihiro Yoshimura |
Address | 1-1 Mitsuzawanishi-cho Kanagawa-ku Yokohama city Kanagawa Kanagawa Japan 221-0855 |
Telephone | +81-45-316-4580 |
yymole@gmailc.om | |
Affiliation | Yokohama Municipal Citizen's Hospital |