Skin test and flow cytometry in healthy volunteers to establish the method for determining causative drug of perioperative anaphylaxis: A preliminary study

JRCT ID: jRCT1031200312

Registered date:19/01/2021

Basic Information

• Recruitment status: Complete
• Health condition(s) or Problem(s) studied: anaphylaxis
• Date of first enrollment: 21/05/2015
• Target sample size: 52
• Study type: Interventional
• Intervention(s): Basophil activation test

Outcome(s)

• Primary Outcome: Seeking the optimum concentration of drugs for skin test and BAT

Key inclusion & exclusion criteria

• Age minimum: >= 20age old
• Age maximum: Not applicable
• Gender: Both

Include criteria

1) A volunteer who is 20 years or older
2) Avolunteer whose written consent has been obtained regarding participation in this study

Exclude criteria

1)A pregnant woman /A patient who has a possibility of pregnancy
2)A volunteer taking beta blocker
3)A volunteer taking steroid
4)A volunteer with past history of perioperative anaphylaxis
5)A volunteer to whom a doctor judged inappropriate for participating in this study

Related Information

• Primary Sponsor: Takazawa Tomonori
• Source(s) of Monetary Support: Japan Society for the Promotion of Science