JRCT ID: jRCT1031190027
Registered date:22/05/2019
Should ARB/CAB combination tablets be continued or withheld preoperatively?
Basic Information
| Recruitment status | Complete |
|---|---|
| Health condition(s) or Problem(s) studied | Hypertension under treatment with ARB/CAB combination tablets |
| Date of first enrollment | 02/05/2019 |
| Target sample size | 120 |
| Countries of recruitment | |
| Study type | Interventional |
| Intervention(s) | Randomization into continuing and withholding ARB/CAB combination tablets before general anesthesia and surgery |
Outcome(s)
| Primary Outcome | Perioperative changes in blood pressure and requirements of vasoactive agents |
|---|---|
| Secondary Outcome | Incidences of perioperative complications, including profound hypotension, profound hypertension, and electrocardiographic abnormalities |
Key inclusion & exclusion criteria
| Age minimum | >= 20age old |
|---|---|
| Age maximum | <= 80age old |
| Gender | Both |
| Include criteria | Surgical patients with hypertension treated with ARB/CAB combination tablets |
| Exclude criteria | Patients having severe comorbidities, including heart disease, and those scheduled for major surgery including cardiac surgery |
Related Information
| Primary Sponsor | Hayashida Masakazu |
|---|---|
| Secondary Sponsor | Inada Eiichi |
| Source(s) of Monetary Support | Juntendo University Hospital |
| Secondary ID(s) |
Contact
| Public contact | |
| Name | Masakazu Hayashida |
| Address | Hongo 3-1-3, Bunkyo-ku, Tokyo 113-8431, Japan Tokyo Japan 113-8431 |
| Telephone | +81-3-3813-3111 |
| hayashidatoday@yahoo.co.jp | |
| Affiliation | Juntendo University Hospital |
| Scientific contact | |
| Name | Masakazu Hayashida |
| Address | Hongo 3-1-3, Bunkyo-ku, Tokyo 113-8431, Japan Tokyo Japan 113-8431 |
| Telephone | +81-3-3813-3111 |
| hayashidatoday@yahoo.co.jp | |
| Affiliation | Juntendo University Hospital |